Conditions we see
- Marfan syndrome
- Vascular Ehlers-Danlos syndrome
- Loeys-Dietz syndrome
- Familial thoracic aortic aneurysm and dissection
- Bicuspid aortic valve with associated aortopathy
How care differs
Aneurysms are repaired at smaller diameters, blood pressure is controlled more tightly, contact sport and heavy lifting are usually avoided, and imaging is repeated at set intervals for life.
First-degree relatives should be screened, since a diagnosis in one family member frequently uncovers silent disease in another.
Research
Prof Sultan leads an international consortium combining genetics, proteomics, biomarkers, tissue biomechanics and advanced imaging to build better diagnostic tools for cardiovascular connective tissue disorders, particularly aortic and cervical dissection.
